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The class I biological cabinet is defined as an open fronted, negative pressure ventilated cabinet for personnel and environmental protection, with an unrecirculated air flow away from the operator. Class I cabinets are very similar in nature to a chemical fume hood except that they have a high efficiency particulate air
(HEPA) filter on their exhaust outlet, and they may or may not be connected to an exhaust duct system. One limitation of the Class I cabinet is that is does not provide product protection.
This cabinet may be used in three operational modes: with a full width open front, with an installed front closure panel not equipped with gloves, and with an installed front closure panel equipped with arm-length rubber gloves.
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